Article
Progressive inactivation of the expression of an erythroid transcriptional factor in GM- and G-CSF-dependent myeloid cell lines.
Nucleic acids research - 11 Dec 1990
Crotta S, Nicolis S, Ronchi A, Ottolenghi S, Ruzzi L, Shimada Y, Migliaccio A R, Migliaccio G
Abstract excerpt
The transcriptional binding protein NFE-1 (also called GF-1 and Ery-f1) is thought to play a necessary, but not sufficient, role in the regulation of differentiation-related gene expression in a subset of hematopoietic lineages (erythroid, megakaryocytic, and basophil-mast cell). In order to clarify the mechanism which underlies the lineage-specificity of the NFE-1 expression, as well as the relationship between...
Topics
- Animals
- Blotting, Northern
- DNA-Binding Proteins
- Erythroid-Specific DNA-Binding Factors
- Erythropoietin
- GATA1 Transcription Factor
- Gene Expression Regulation
- Globins
- Granulocyte Colony-Stimulating Factor
- Granulocyte-Macrophage Colony-Stimulating Factor