Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcriptional program of terminal granulocytic differentiation

29 Oct 2004

Abstract excerpt

To characterize the transcriptional program that governs terminal granulocytic differentiation in vivo, we performed comprehensive microarray analyses of human bone marrow populations highly enriched in promyelocytes (PMs), myelocytes/metamyelocytes (MYs), and neutrophils (bm-PMNs). These analyses identified 11 310 genes involved in differentiation, of which 6700 were differentially regulated, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15514007
DOI: 10.1182/blood-2004-08-3346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcriptional program of terminal granulocytic differentiationPMID 15514007Read ↗

Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells.Semantic proximity Read ↗

Epigenomic and functional dynamics of human bone marrow myeloid differentiation to mature blood neutrophilsSemantic proximity Read ↗

Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsisSemantic proximity Read ↗

Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donorsSemantic proximity Read ↗

A map of gene expression in neutrophil-like cell linesSemantic proximity Read ↗

NB4 cells show bilineage potential and an aberrant pattern of neutrophil secondary granule protein gene expressionSemantic proximity Read ↗

A molecular atlas of human granulopoiesisSemantic proximity Read ↗

Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation.Semantic proximity Read ↗

Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of cytokine-stimulated CD34+ human marrow cells in vitro.Semantic proximity Read ↗

A map of gene expression in neutrophil-like cell linesSemantic proximity Read ↗

Zfp263 is a transcriptional checkpoint of neutrophil developmentSemantic proximity Read ↗

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.