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Article

Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.

American journal of physiology. Cell physiology - 1 Jul 2003

Afroze Talat, Yang Li L, Wang Changsen, Gros Robert, Kalair Waseem, Hoque Abu N, Mungrue Imran N, Zhu Ziping, Husain Mansoor

Abstract excerpt

Calcineurin mediates repression of plasma membrane Ca2+-ATPase-4 (PMCA4) expression in neurons, whereas c-Myb is known to repress PMCA1 expression in vascular smooth muscle cells (VSMC). Here, we describe a novel mouse VSMC line (MOVAS) in which 45Ca efflux rates decreased 50%, fura 2-AM-based intracellular Ca2+ concentrations ([Ca2+]i) increased twofold, and real-time RT-PCR and Western blot revealed a...

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Identifiers

PMID: 12660151
DOI: 10.1152/ajpcell.00518.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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