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Article

Calcium regulation of GM-CSF by calmodulin-dependent kinase II phosphorylation of Ets1.

Molecular biology of the cell - 1 Dec 2002

Liu Hebin, Grundström Thomas

Abstract excerpt

The multipotent cytokine granulocyte macrophage-colony stimulating factor (GM-CSF) is involved in particular in the physiological response to infection and in inflammatory responses. GM-CSF is produced by many cell types, including T lymphocytes responding to T-cell receptor activation and mantle...

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Identifiers

PMID: 12475968
DOI: 10.1091/mbc.e02-03-0149
PMCID: PMC138649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12475968-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Calcium regulation of GM-CSF by calmodulin-dependent kinase II phosphorylation of Ets1.PMID 12475968Read ↗

ETS1 transactivates the human GM-CSF promoter in Jurkat T cells stimulated with PMA and ionomycin.Semantic proximity Read ↗

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Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin.Semantic proximity Read ↗

The calcineurin-NFAT pathway negatively regulates megakaryopoiesisSemantic proximity Read ↗

G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation.Semantic proximity Read ↗

A calmodulin-binding site on cyclin E mediates Ca2+-sensitive G1/s transitions in vascular smooth muscle cells.Semantic proximity Read ↗

Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation.Semantic proximity Read ↗

Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expressionSemantic proximity Read ↗

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