Article
Association between glutathione S-transferase p1 polymorphisms and lung cancer risk in Caucasians: a case-control study.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2003
Wang Yunfei, Spitz Margaret R, Schabath Matthew B, Ali-Osman Francis, Mata Hilario, Wu Xifeng
Abstract excerpt
Glutathione transferases (GSTs), a multiple gene family of phase II enzymes, catalyze detoxifying endogenous reactions with glutathione and protect cellular macromolecules from damage caused by cytotoxic and carcinogenic agents. Glutathione S-transferase p1 (GSTP1), the most abundant GST isoform...
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