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Article

Ocular hypertension in mice with a targeted type I collagen mutation.

Investigative ophthalmology & visual science - 1 Apr 2003

Aihara Makoto, Lindsey James D, Weinreb Robert N

Abstract excerpt

PURPOSE: To evaluate intraocular pressure (IOP) in transgenic mice with a targeted mutation in the gene for the alpha1 subunit of collagen type I. METHODS: Homozygous B6; 129-Cola1(tm1Jae) mice and corresponding wild-type mice were anesthetized. A fluid-filled glass microneedle connected to a pressure transducer was then inserted through the cornea into the anterior chamber to measure IOP. All measurements were...

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Identifiers

PMID: 12657595
DOI: 10.1167/iovs.02-0759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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