Article
Ocular abnormalities in transgenic mice harboring mutations in the type II collagen gene.
European journal of ophthalmology - 1 Jan 2000
Ihanamäki T, Metsäranta M, Rintala M, Vuorio E, Sandberg-Lall M
Abstract excerpt
PURPOSE: To characterize the morphological changes in the eyes of transgenic mice harboring different mutations in type II collagen gene to elucidate the function of this collagen in the eye, and to find out whether these animals could function as models for the human arthro-ophthalmopathies of the Kniest, Stickler and Wagner types. METHODS: Three genetically engineered mouse lines representing two types of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
