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Article

Transgenic RNAi in mouse oocytes: a simple and fast approach to study gene function.

Developmental biology - 1 Apr 2003

Stein Paula, Svoboda Petr, Schultz Richard M

Abstract excerpt

Double-strand RNA (dsRNA)-mediated posttranscriptional gene silencing, also known as RNA interference (RNAi), is a powerful tool to inhibit gene expression in several experimental model systems, including Arabidopsis, Caenorhabditis, and Drosophila. We previously described that the microinjection of Mos dsRNA into fully grown mouse oocytes results in the specific degradation of Mos mRNA in a time- and...

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Identifiers

PMID: 12654301
DOI: 10.1016/s0012-1606(02)00122-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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