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Article

Degradation of maternal mRNA in mouse embryos: Selective degradation of specific mRNAs after fertilization

10 Aug 2005

Abstract excerpt

During oogenesis, mRNA is actively transcribed and accumulated in growing oocytes, but this transcription stops before the oocytes grow to their full size. The accumulated maternal mRNA is used for protein synthesis in the oocytes during meiotic maturation and even in the embryos to sustain development after fertilization. Therefore, the degradation of accumulated maternal mRNA starts during meiotic maturation,...

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PMID: 16094646
DOI: 10.1002/mrd.20340

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