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Article

Induction of invasive phenotype by Casodex in hormone-sensitive prostate cancer cells.

The Journal of steroid biochemistry and molecular biology - 1 Dec 2002

Zhan Ping, Lee Edmund Chun Yu, Packman Kathryn, Tenniswood Martin

Abstract excerpt

The cellular mechanisms of anti-androgen-induced tumor regression have not been investigated in great detail. We have compared the induction of cell death in the androgen-dependent, non-invasive LNCaP prostate cancer cell line by Casodex and TNF-alpha. Both agents induce a dose and time-dependent...

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Identifiers

PMID: 12650706
DOI: 10.1016/s0960-0760(02)00275-3

Genes

TNF
MMP2
TIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12650706-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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