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Article

Suppression of hepatocyte growth factor activator inhibitor-1 leads to a more aggressive phenotype of prostate cancer cells in vitro.

International journal of molecular medicine - 1 Oct 2007

Sanders Andrew J, Parr Christian, Mason Malcolm D, Jiang Wen G

Abstract excerpt

The hepatocyte growth factor (HGF) pathway has been well documented as playing a vital role in the progression and development of many different types of human cancers; as such this pathway is usually tightly regulated. In cancer cells, the regulation of this pathway has been shown to be disrupted, allowing an increase in activation of pro-HGF to active HGF. There are a number of molecules capable of activating...

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PMID: 17786295

Genes

HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Suppression of hepatocyte growth factor activator inhibitor-1 leads to a more aggressive phenotype of prostate cancer cells in vitro.PMID 17786295Read ↗

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