Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The emergence of protocadherin-PC expression during the acquisition of apoptosis-resistance by prostate cancer cells.

Oncogene - 7 Nov 2002

Chen Min-Wei, Vacherot Francis, De La Taille Alexandre, Gil-Diez-De-Medina Sixtina, Shen Ruoqian, Friedman Richard A, Burchardt Martin, Chopin Dominique K, Buttyan Ralph

Abstract excerpt

In order to identify gene products associated with the development of acquired therapeutic resistance by prostate cancer cells, we created two novel apoptosis-resistant prostate cancer cell lines, LNCaP-TR (phorbol-ester [TPA]-Resistant) and LNCaP-SSR (Serum Starvation-Resistant) by repeated transient exposure of cultured human LNCaP cells to apoptotic stimuli followed by expansion of surviving cell populations....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgens
Share to Culture Media, Serum-Free

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Neoplasm Transplantation

Share to Neoplasms, Hormone-Dependent

Share to Protein Sorting Signals

Share to Protocadherins

Share to Tetradecanoylphorbol Acetate

Source

Identifiers

PMID: 12420223
DOI: 10.1038/sj.onc.1205991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The emergence of protocadherin-PC expression during the acquisition of apoptosis-resistance by prostate cancer cells.PMID 12420223Read ↗

Cross modulation between the androgen receptor axis and protocadherin-PC in mediating neuroendocrine transdifferentiation and therapeutic resistance of prostate cancer.Semantic proximity Read ↗

Apoptosis evasion: The role of survival pathways in prostate cancer progression and therapeutic resistanceSemantic proximity Read ↗

[Hormone-resistant epithelial cancer of the prostate].Semantic proximity Read ↗

Androgen Deprivation-Induced Senescence Promotes Outgrowth of Androgen-Refractory Prostate Cancer CellsSemantic proximity Read ↗

Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activationSemantic proximity Read ↗

Phenotypic variations of TRAIL sensitivity in cloned populations of prostate cancer cells.Semantic proximity Read ↗

Low-dose 12-O-tetradecanoylphorbol-13-acetate enhances tumor necrosis factor related apoptosis-inducing ligand induced apoptosis in prostate cancer cells.Semantic proximity Read ↗

miR-130a activates apoptotic signaling through activation of caspase-8 in taxane-resistant prostate cancer cellsSemantic proximity Read ↗

Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate.Semantic proximity Read ↗

Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis.Semantic proximity Read ↗

Differential expression of genes induced by resveratrol in LNCaP cells: P53‐mediated molecular targetsSemantic proximity Read ↗

Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.