Article
Genome screen in familial intracranial aneurysm.
BMC medical genetics - 13 Jan 2009
Foroud Tatiana, Sauerbeck Laura, Brown Robert, Anderson Craig, Woo Daniel, Kleindorfer Dawn, Flaherty Matthew L, Deka Ranjan, Hornung Richard, Meissner Irene, Bailey-Wilson Joan E, Langefeld Carl, Rouleau Guy, Connolly E Sander, Lai Dongbing, Koller Daniel L, Huston John, Broderick Joseph P
Abstract excerpt
BACKGROUND: Individuals with 1st degree relatives harboring an intracranial aneurysm (IA) are at an increased risk of IA, suggesting genetic variation is an important risk factor. METHODS: Families with multiple members having ruptured or unruptured IA were recruited and all available medical records and imaging data were reviewed to classify possible IA subjects as definite, probable or possible IA or not a...
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