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Article

Additive Method for the Prediction of Protein−Peptide Binding Affinity. Application to the MHC Class I Molecule HLA-A*0201

12 Apr 2002

Abstract excerpt

A method has been developed for prediction of binding affinities between proteins and peptides. We exemplify the method through its application to binding predictions of peptides with affinity to major histocompatibility complex class I molecule HLA-A*0201. The method is named "additive" because it is based on the assumption that the binding affinity of a peptide could be presented as a sum of the contributions...

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PMID: 12645903
DOI: 10.1021/pr015513z

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