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Article

Activation of myelin genes during transdifferentiation from melanoma to glial cell phenotype.

The Journal of biological chemistry - 14 Mar 2003

Slutsky Shalom G, Kamaraju Anil K, Levy Alon M, Chebath Judith, Revel Michel

Abstract excerpt

Induction of myelin genes occurs around birth in the last stage of Schwann cells differentiation and is reactivated in case of nerve injury. Previous studies showed that activation of the gp130 receptor system, using as ligand interleukin-6 fused to its soluble receptor (IL6RIL6), causes induction of myelin genes such as myelin basic protein (MBP) and myelin protein zero (Po) in embryonic dorsal root ganglia...

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Identifiers

PMID: 12643284
DOI: 10.1074/jbc.m210569200

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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