Article
Mechanisms of transcriptional activation of the col6a1 gene during Schwann cell differentiation.
Mechanisms of development - 1 Apr 2001
Vitale P, Braghetta P, Volpin D, Bonaldo P, Bressan G M
Abstract excerpt
A transgenic mouse line expressing the lacZ reporter under the control of a regulatory region of the col6a1 gene has been used to investigate differentiation of Schwann cells. The data suggest that: (1) activation of col6a1 gene transcription in the peripheral nervous system is part of the differentiation program of Schwann cells from neural crest cells stimulated by neuregulins; (2) once the Schwann cell...
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