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Article

The RasGAP-associated endoribonuclease G3BP assembles stress granules.

The Journal of cell biology - 17 Mar 2003

Tourrière Helene, Chebli Karim, Zekri Latifa, Courselaud Brice, Blanchard Jean Marie, Bertrand Edouard, Tazi Jamal

Abstract excerpt

Stress granules (SGs) are formed in the cytoplasm in response to various toxic agents, and are believed to play a critical role in the regulation of mRNA metabolism during stress. In SGs, mRNAs are stored in an abortive translation initiation complex that can be routed to either translation initiation or degradation. Here, we show that G3BP, a phosphorylation-dependent endoribonuclease that interacts with RasGAP,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12642610
DOI: 10.1083/jcb.200212128
PMCID: PMC2173781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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