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Article

Bmp2 deletion causes an amelogenesis imperfecta phenotype via regulating enamel gene expression.

Journal of cellular physiology - 1 Aug 2015

Guo Feng, Feng Junsheng, Wang Feng, Li Wentong, Gao Qingping, Chen Zhuo, Shoff Lisa, Donly Kevin J, Gluhak-Heinrich Jelica, Chun Yong Hee Patricia, Harris Stephen E, MacDougall Mary, Chen Shuo

Abstract excerpt

Although Bmp2 is essential for tooth formation, the role of Bmp2 during enamel formation remains unknown in vivo. In this study, the role of Bmp2 in regulation of enamel formation was investigated by the Bmp2 conditional knock out (Bmp2 cKO) mice. Teeth of Bmp2 cKO mice displayed severe and profo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25545831
DOI: 10.1002/jcp.24915
PMCID: PMC4469356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-25545831-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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