Article
Increased Young's modulus and hardness of Col1a2oim dentin.
Journal of dental research - 1 Nov 2006
Lopez Franco G E, Huang A, Pleshko Camacho N, Stone D S, Blank R D
Abstract excerpt
Mice harboring the Col1a2(oim) mutation (oim) express dentinogenesis imperfecta. To determine the effect of Col1a2 genotype on tissue mechanical properties, we compared Young's modulus and hardness of dentin in the 3 Col1a2 genotypes. Upper incisors were tested by nanoindentation. Genotype had a significant effect on Young's modulus, but there was not a simple mutant allele dosage relationship. The effect of...
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