Article
Differential effects of corticosteroids during different stages of dendritic cell maturation.
European journal of immunology - 1 Apr 2000
Matyszak M K, Citterio S, Rescigno M, Ricciardi-Castagnoli P
Abstract excerpt
Dendritic cell (DC) maturation is a complex process involving many cell functions. We have studied how the exposure of DC to corticosteroids at different stages of DC maturation affects priming and the expansion of different subsets of CD4(+) T cells. Growth factor- dependent DC lines and fresh bone marrow-derived DC were used. When exposed to inflammatory stimuli, immature DC previously treated with...
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