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Article

Characterization and Selection of HIV-1 Subtype C Isolates for Use in Vaccine Development

1 Feb 2003

Abstract excerpt

HIV-1 genetic diversity among circulating strains presents a major challenge for HIV-1 vaccine development, particularly for developing countries where less sequence information is available. To identify representative viruses for inclusion in candidate vaccines targeted for South Africa, we applied an efficient sequence survey strategy to samples from recently and chronically infected persons residing in...

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PMID: 12639249
DOI: 10.1089/088922203762688649

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