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Article

Alphavirus replicon particles as candidate HIV vaccines.

IUBMB life - 1 Jan 2000

Davis Nancy L, West Ande, Reap Elizabeth, MacDonald Gene, Collier Martha, Dryga Sergey, Maughan Maureen, Connell Mary, Walker Chris, McGrath Kathryn, Cecil Chad, Ping Li-Hua, Frelinger Jeff, Olmsted Robert, Keith Paula, Swanstrom Ronald, Williamson Carolyn, Johnson Philip, Montefiori David, Johnston Robert E

Abstract excerpt

Replicon particles based on Venezuelan equine encephalitis virus (VEE) contain a self-replicating RNA encoding the VEE replicase proteins and expressing a gene of interest in place of the viral structural protein genes. Structural proteins for packaging of replicon RNA into VEE replicon particles (VRPs) are expressed from separate helper RNAs. Aspects of the biology of VEE that are exploited in VRP vaccines...

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Identifiers

PMID: 12120997
DOI: 10.1080/15216540212657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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