Article
Evaluation of envelope vaccines derived from the South African subtype C human immunodeficiency virus type 1 TV1 strain.
Journal of virology - 1 Nov 2005
Lian Ying, Srivastava Indresh, Gómez-Román V Rául, Zur Megede Jan, Sun Yide, Kan Elaine, Hilt Susan, Engelbrecht Susan, Himathongkham Sunee, Luciw Paul A, Otten Gillis, Ulmer Jeffrey B, Donnelly John J, Rabussay Dietmar, Montefiori David, van Rensburg Estrelita Janse, Barnett Susan W
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) subtype C infections are on the rise in Sub-Saharan Africa and Asia. Therefore, there is a need to develop an HIV vaccine capable of eliciting broadly reactive immune responses against members of this subtype. We show here that modified HIV envelope (env) DNA vaccines derived from the South African subtype C TV1 strain are able to prime for humoral responses in rabbits...
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