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Article

Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis.

The Journal of biological chemistry - 16 May 2003

Rodeheffer Matthew S, Shadel Gerald S

Abstract excerpt

The amino-terminal domain (ATD) of Saccharomyces cerevisiae mitochondrial RNA polymerase has been shown to provide a functional link between transcription and post-transcriptional events during mitochondrial gene expression. This connection is mediated in large part by its interactions with the matrix protein Nam1p and, based on genetic phenotypes, the mitochondrial membrane protein Sls1p. These observations led...

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Identifiers

PMID: 12637560
DOI: 10.1074/jbc.M301399200
PMCID: PMC2606056

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