Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase.

Proceedings of the National Academy of Sciences of the United States of America - 6 Jul 1999

Wang Y, Shadel G S

Abstract excerpt

Mitochondrial RNA (mtRNA) polymerases are related to bacteriophage RNA polymerases, but contain a unique amino-terminal extension of unknown origin and function. In addition to harboring mitochondrial targeting information, we show here that the amino-terminal extension of yeast mtRNA polymerase is required for a mtDNA maintenance function that is separable from the known RNA polymerization activity of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages
Share to DNA-Directed RNA Polymerases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Genome, Fungal

Share to Mitochondria

Share to Plasmids

Share to Sequence Deletion

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 10393945
DOI: 10.1073/pnas.96.14.8046
PMCID: PMC22185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase.PMID 10393945Read ↗

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation.Semantic proximity Read ↗

Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis.Semantic proximity Read ↗

A non-radioactive DNA synthesis assay demonstrates that elements of the Sigma 1278b Mip1 mitochondrial DNA polymerase domain and C-terminal extension facilitate robust enzyme activity.Semantic proximity Read ↗

DNA polymerases in the mitochondria: A critical review of the evidence.Semantic proximity Read ↗

Biochemical, cellular and molecular identification of DNA polymerase α in yeast mitochondria.Semantic proximity Read ↗

Precise mapping and characterization of the RNA primers of DNA replication for a yeast hypersuppressive petite by in vitro capping with guanylyltransferase.Semantic proximity Read ↗

Mechanisms of mammalian mitochondrial transcriptionSemantic proximity Read ↗

Hitting the brakes: termination of mitochondrial transcription.Semantic proximity Read ↗

Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span.Semantic proximity Read ↗

Multiple functions of yeast mitochondrial transcription factor Mtf1p during initiation.Semantic proximity Read ↗

DNA replication and transcription in mammalian mitochondria.Semantic proximity Read ↗

A Saccharomyces cerevisiae mitochondrial transcription factor, sc-mtTFB, shares features with sigma factors but is functionally distinct.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.