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Article

Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.

International journal of oncology - 1 Apr 2003

Yokoyama Kazuhiro, Kamata Nobuyuki, Fujimoto Ryoichi, Tsutsumi Satoshi, Tomonari Mayumi, Taki Masayuki, Hosokawa Hiroyoshi, Nagayama Masaru

Abstract excerpt

Loss of E-cadherin expression is a major characteristic of highly invasive and metastatic cancers. Epithelial-mesenchymal transition (EMT) has been advocated to be a causative mechanism for the suppression of E-cadherin and tumor progression. Snail is a zinc finger transcription factor that triggers the EMT and is one of the recently identified E-cadherin repressors. The reverse correlation of Snail and...

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PMID: 12632084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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