Article

Ciliogenic pancreatopathy reveals a link between ciliopathies and exocrine pancreatic disease

2026-01-29

Abstract excerpt

<h4>Background</h4> While pancreatic cysts have been described in syndromic ciliopathies, the pancreas is not commonly recognized as a target organ. However, several ciliary gene knockout mouse models develop a pancreatic phenotype combining acinar atrophy and adipocyte accumulation, hereby called adipopancreatosis, suggesting a link between ciliary dysfunction and pancreatic disease. <h4>Objective</h4> We inves...

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Literature Corpus work: c3ef7d76-8a67-5647-b4a0-0f39bfa96fd8
DOI: 10.64898/2026.01.27.701983

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