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Article

The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.

The EMBO journal - 17 Mar 2003

Schäfer Thorsten, Strauss Daniela, Petfalski Elisabeth, Tollervey David, Hurt Ed

Abstract excerpt

Recent reports have increased our knowledge of the consecutive steps during 60S ribosome biogenesis substantially, but 40S subunit formation is less well understood. Here, we investigate the maturation of nucleolar 90S pre-ribosomes into cytoplasmic 40S pre-ribosomes. During the transition from 90S to 40S particles, the majority of non-ribosomal proteins (approximately 30 species) dissociate, and significantly...

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Identifiers

PMID: 12628929
DOI: 10.1093/emboj/cdg121
PMCID: PMC151049

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