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Article

Yeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturation.

The Journal of biological chemistry - 2 Nov 2012

Fernández-Pevida Antonio, Rodríguez-Galán Olga, Díaz-Quintana Antonio, Kressler Dieter, de la Cruz Jesús

Abstract excerpt

Most ribosomal proteins play important roles in ribosome biogenesis and function. Here, we have examined the contribution of the essential ribosomal protein L40 in these processes in the yeast Saccharomyces cerevisiae. Deletion of either the RPL40A or RPL40B gene and in vivo depletion of L40 impair 60 S ribosomal subunit biogenesis. Polysome profile analyses reveal the accumulation of half-mers and a moderate...

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Identifiers

PMID: 22995916
DOI: 10.1074/jbc.M112.400564
PMCID: PMC3488107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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