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Article

Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae.

Antimicrobial agents and chemotherapy - 1 Jan 2001

Depardieu F, Courvalin P

Abstract excerpt

Streptococcus pneumoniae clinical isolate BM4455 was resistant to 16-membered macrolides and to streptogramins. This unusual resistance phenotype was due to an A(2062)C (Escherichia coli numbering) mutation in domain V of the four copies of 23S rRNA.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Ribosomal, 23S

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Identifiers

PMID: 11120988
DOI: 10.1128/AAC.45.1.319-323.2001
PMCID: PMC90283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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