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[Construction and function analysis of a CTAR-2 region mutant of the Epstein-Barr virus-encoded latent membrane protein-1].

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica - 1 Mar 2003

He Zhi-Min, Chen Zhu-Chu

Abstract excerpt

To investigate the activating sites and functional mechanism of Epstein-Barr virus(EBV)-latent membrane protein-1(LMP1), a mutant type LMP1(mt-LMP1) was made by PCR methods, replacing the amino acid residues YYD with ID in carboxy terminal activating region-2 (CTAR-2) at position 384-386 codons. The mt-LMP1 and wild type LMP1 (wt-LMP1) were cotransfected with transcription factor NF-kappa B or AP-1 luciferase...

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PMID: 12621551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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