Article
The 30-base-pair deletion in Chinese variants of the Epstein-Barr virus LMP1 gene is not the major effector of functional differences between variant LMP1 genes in human lymphocytes.
Journal of virology - 1 May 1998
Johnson R J, Stack M, Hazlewood S A, Jones M, Blackmore C G, Hu L F, Rowe M
Abstract excerpt
One group of sequence variants of Epstein-Barr virus is characterized by a 10-amino-acid deletion within the CTAR-2 functional domain of the latent membrane protein, LMP1. A role for this deletion in enhancing the tumorigenicity of the viral oncogene in rodent fibroblasts was recently demonstrated. We examined the effect of this deletion upon LMP1 function in four human lymphoid cell lines by using three natural...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.