Article
The Caenorhabditis elegans heterochronic gene pathway controls stage-specific transcription of collagen genes.
Development (Cambridge, England) - 1 Aug 1995
Liu Z, Kirch S, Ambros V
Abstract excerpt
In Caenorhabditis elegans, the terminal differentiation of the hypodermal cells occurs at the larval-to-adult molt, and is characterized in part by the formation of a morphologically distinct adult cuticle. The timing of this event is controlled by a pathway of heterochronic genes that includes the relatively direct regulatory gene, lin-29, and upstream genes lin-4, lin-14 and lin-28. Using northern analysis to...
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