Article
Association of interleukin-10 gene single nucleotide polymorphisms with rheumatoid arthritis in a Chinese population.
Postgraduate medical journal - 1 May 2018
Zhang Tian-Ping, Lv Tian-Tian, Xu Shu-Zhen, Pan Hai-Feng, Ye Dong-Qing
Abstract excerpt
PURPOSE OF THE STUDY: Increasing numbers of studies show that interleukin (IL)-10 plays a key role in the pathogenesis of autoimmune diseases including rheumatoid arthritis (RA) and acts as an immunomodulatory cytokine. The purpose of the present study was to analyse the relationship between gene single nucleotide polymorphisms (SNPs) in the IL-10 gene and RA susceptibility. STUDY DESIGN: We genotyped three SNPs...
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