Article
Sarcoidosis susceptibility and resistance HLA-DQB1 alleles in African Americans.
American journal of respiratory and critical care medicine - 1 May 2003
Iannuzzi Michael C, Maliarik Mary J, Poisson Laila M, Rybicki Benjamin A
Abstract excerpt
Sarcoidosis, in the United States, more commonly and severely affects African Americans. HLA associations with sarcoidosis have been reported, but most studies used case-control designs, which may produce biased results because of population stratification. We examined transmission of HLA-DQB1 alleles in 225 African American families with at least one offspring with sarcoidosis. Of five low-resolution HLA-DQB1...
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