Article
Transcriptional regulation of yeast peroxiredoxin gene TSA2 through Hap1p, Rox1p, and Hap2/3/5p.
Free radical biology & medicine - 1 Mar 2003
Wong Chi-Ming, Ching Yick-Pang, Zhou Yuan, Kung Hsiang-Fu, Jin Dong-Yan
Abstract excerpt
In Saccharomyces cerevisiae, the transcription of peroxiredoxin gene TSA2 is responsive to various reactive oxygen and nitrogen species. Redox-regulated transcriptional activators Yap1p, Skn7p, Msn2p/Msn4p have been shown to play a role in regulating TSA2 expression. In this study we show that the transcription of TSA2 is under complex control involving additional transcription factors Hap1p, Rox1p, and...
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