Article
Surface expression of CC- and CXC-chemokine receptors on leucocyte subsets in inflammatory joint diseases.
Clinical and experimental immunology - 1 Dec 2001
Brühl H, Wagner K, Kellner H, Schattenkirchner M, Schlöndorff D, Mack M
Abstract excerpt
Chemokine receptors play a crucial role in the recruitment of leucocyte subsets into inflamed tissue. Using FACS analysis we have studied the surface expression of different CC- and CXC-chemokine receptors on synovial fluid (SF) and peripheral blood leucocytes from 20 patients with various forms of arthritis. In the SF the majority T cells stained positive for CCR5 (93%) and CCR2 (57%), compared to the peripheral...
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