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Article

Polymorphism of the insulin gene is associated with increased prostate cancer risk.

British journal of cancer - 27 Jan 2003

Ho G Y F, Melman A, Liu S-M, Li M, Yu H, Negassa A, Burk R D, Hsing A W, Ghavamian R, Chua S C

Abstract excerpt

High insulin levels are linked with increased cancer risk, including prostate cancer. We examined the associations between prostate cancer with polymorphisms of the insulin gene (INS) and its neighbouring genes, tyrosine-hydroxylase and IGF-II (TH and IGF2). In this study, 126 case-control pairs matched on age, race, and countries of origin were genotyped for +1127 INS-PstI in INS, -4217 TH-PstI in TH, and +3580...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12610512
DOI: 10.1038/sj.bjc.6600747
PMCID: PMC2377060

Genes

INS
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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