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Article

Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children.

Diabetes care - 1 Mar 2003

Mochizuki Mie, Amemiya Shin, Kobayashi Kisho, Kobayashi Koji, Shimura Yoshie, Ishihara Toshihide, Nakagomi Yoshiko, Onigata Kazumichi, Tamai Shinya, Kasuga Akira, Nanazawa Shinpei

Abstract excerpt

OBJECTIVE: To clarify the role of the T-lymphocyte-associated-4 (CTLA-4) polymorphism in the susceptibility to child-onset type 1 diabetes with regard to its clinical characteristics and complications with autoimmune thyroid disease (AITD) in the Japanese population. RESEARCH DESIGN AND METHODS: The CTLA-4 49 A/G polymorphism was detected by the PCR-restriction fragment-length polymorphism (RFLP) method in 97...

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Identifiers

PMID: 12610047
DOI: 10.2337/diacare.26.3.843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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