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Article

Association of CTLA-4 polymorphism with positive anti-GAD antibody in Japanese subjects with type 1 diabetes mellitus.

Clinical endocrinology - 1 Dec 1999

Hayashi H, Kusaka I, Nagasaka S, Kawakami A, Rokkaku K, Nakamura T, Saito T, Higashiyama M, Honda K, Ishikawa S E

Abstract excerpt

OBJECTIVE: CTLA-4, expressed on activated T cells, is thought to be a negative regulator of T cell function. Its gene (2q33) may confer genetic susceptibility to type 1 diabetes mellitus (IDDM12). The present study was undertaken to clarify the role of CTLA-4 gene polymorphism in Japanese subject...

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Source

Identifiers

PMID: 10619986
DOI: 10.1046/j.1365-2265.1999.00890.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10619986-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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