Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Peptide Inhibitors of Angiotensin-converting Enzyme 2

25 Apr 2003

Abstract excerpt

Angiotensin-converting enzyme 2 (ACE2), a recently identified human homolog of ACE, is a novel metallocarboxypeptidase with specificity, tissue distribution, and function distinct from those of ACE. ACE2 may play a unique role in the renin-angiotensin system and mediate cardiovascular and renal function. Here we report the discovery of ACE2 peptide inhibitors through selection of constrained peptide libraries...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Protein Hydrolysis and Bioactive Peptides
Share to Renin-Angiotensin System Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12606557
DOI: 10.1074/jbc.m212934200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Peptide Inhibitors of Angiotensin-converting Enzyme 2PMID 12606557Read ↗

Directed evolution of angiotensin-converting enzyme 2 (ACE2) peptidase activity profiles for therapeutic applicationsSemantic proximity Read ↗

Inhibitory antibodies to human angiotensin-converting enzyme: fine epitope mapping and mechanism of action.Semantic proximity Read ↗

Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): identification of selective inhibitors of collagenase-1 (metalloproteinase 1 (MMP-1)).Semantic proximity Read ↗

The influence of angiotensin converting enzyme mutations on the kinetics and dynamics of N-domain selective inhibition.Semantic proximity Read ↗

Selective inhibition of the C-domain of angiotensin I converting enzyme by bradykinin potentiating peptides.Semantic proximity Read ↗

Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activitySemantic proximity Read ↗

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulationSemantic proximity Read ↗

Iterative optimization of high-affinity protease inhibitors using phage display. 2. Plasma kallikrein and thrombin.Semantic proximity Read ↗

Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme.Semantic proximity Read ↗

Leveraging Molecular Heterogeneity of the Vascular Endothelium for Targeted Drug Delivery and ImagingSemantic proximity Read ↗

Peptide-Based Inhibitors of ADAM and ADAMTS MetalloproteinasesSemantic proximity Read ↗

Analysis of an engineered plasma kallikrein inhibitor and its effect on contact activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.