Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme.

Protein science : a publication of the Protein Society - 1 Aug 2021

Popova Isolda A, Lubbe Lizelle, Petukhov Pavel A, Kalantarov Gavriil F, Trakht Ilya N, Chernykh Elena R, Leplina Olga Y, Lyubimov Alex V, Garcia Joe G N, Dudek Steven M, Sturrock Edward D, Danilov Sergei M

Abstract excerpt

Angiotensin I-converting enzyme (ACE, CD143) plays a crucial role in blood pressure regulation, vascular remodeling, and immunity. A wide spectrum of mAbs to different epitopes on the N and C domains of human ACE have been generated and used to study different aspects of ACE biology, including establishing a novel approach-conformational fingerprinting. Here we characterized a novel set of 14 mAbs, developed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CHO Cells
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cricetulus

Share to Epitope Mapping

Share to Epitopes

Share to Glycosylation

Share to Peptidyl-Dipeptidase A

Share to Protein Domains

Source

Open in PubMed Open full text

Identifiers

PMID: 33931897
DOI: 10.1002/pro.4091
PMCID: PMC8284578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme.PMID 33931897Read ↗

Fine epitope mapping of monoclonal antibodies 9B9 and 3G8 to the N domain of angiotensin-converting enzyme (CD143) defines a region involved in regulating angiotensin-converting enzyme dimerization and shedding.Semantic proximity Read ↗

Fine epitope mapping of monoclonal antibody 5F1 reveals anticatalytic activity toward the N domain of human angiotensin-converting enzyme.Semantic proximity Read ↗

Inhibitory antibodies to human angiotensin-converting enzyme: fine epitope mapping and mechanism of action.Semantic proximity Read ↗

Monoclonal Antibodies 1G12 and 6A12 to the N-domain of human angiotensin-converting enzyme: fine epitope mapping and antibody-based detection of ACE inhibitors in human blood.Semantic proximity Read ↗

Characterization of a new anti-LAG3 monoclonal for immuno-oncologySemantic proximity Read ↗

Identification of IgG3-specific epitope that remedies problem in diagnostic IgG subclass determination due to human genetic variation.Semantic proximity Read ↗

Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain.Semantic proximity Read ↗

Human immunoglobulin allotypesSemantic proximity Read ↗

Phenotyping Angiotensin-Converting Enzyme in Blood: A Necessary Approach for Precision Medicine.Semantic proximity Read ↗

High-Resolution Epitope Mapping and Affinity Binding Analysis Comparing a New Anti-Human LAG3 Rabbit Antibody Clone to the Commonly Used Mouse 17B4 CloneSemantic proximity Read ↗

ACE phenotyping in human heart.Semantic proximity Read ↗

Cloning and characterization of a single-chain fragment of monoclonal antibody to ACE suitable for lung endothelial targeting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.