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MexXY multidrug efflux system of Pseudomonas aeruginosa

1 Jan 2012

Abstract excerpt

Anti-pseudomonas aminoglycosides, such as amikacin and tobramycin, are used in the treatment of Pseudomonas aeruginosa infections. However, their use is linked to the development of resistance. During the last decade, the MexXY multidrug efflux system has been comprehensively studied, and numerous reports of laboratory and clinical isolates have been published. This system has been increasingly recognized as one...

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PMID: 23233851
DOI: 10.3389/fmicb.2012.00408

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