Identification of Pseudomonas aeruginosa genes associated with antibiotic susceptibility.

doi:10.1007/s11427-010-4071-8

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Article

Identification of Pseudomonas aeruginosa genes associated with antibiotic susceptibility.

Science China. Life sciences - 1 Oct 2010

Chen Lin, Yang Liang, Zhao Xingyan, Shen Lixin, Duan Kangmin

Abstract excerpt

Pseudomonas aeruginosa causes acute and chronic infections in humans and these infections are difficult to treat due to the bacteria's high-level of intrinsic and acquired resistance to antibiotics. To address this problem, it is crucial to investigate the molecular mechanisms of antibiotic resistance in this organism. In this study, a P. aeruginosa transposon insertion library of 17000 clones was constructed and...

Topics

Drug Resistance, Microbial
Gene Library
Genes, Bacterial
Humans
Microbial Sensitivity Tests
Mutagenesis, Insertional
Mutation
Polymerase Chain Reaction
Pseudomonas Infections
Pseudomonas aeruginosa

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Open in PubMed

Identifiers

PMID: 20953948
DOI: 10.1007/s11427-010-4071-8

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