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Article

Ubiquitin Proteasome System Role in Diabetes-Induced Cardiomyopathy

19 Oct 2023

Abstract excerpt

This study investigated modifications to the ubiquitin proteasome system (UPS) in a mouse model of type 2 diabetes mellitus (T2DM) and their relationship to heart complications. db/db mice heart tissues were compared with WT mice tissues using RNA sequencing, qRT-PCR, and protein analysis to identify cardiac UPS modifications associated with diabetes. The findings unveiled a distinctive gene profile in the hearts...

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PMID: 37895057
DOI: 10.3390/ijms242015376

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