Article
Linkage analysis of prostate cancer susceptibility: confirmation of linkage at 8p22-23.
Human genetics - 1 Apr 2003
Wiklund Fredrik, Jonsson Björn-Anders, Göransson Ingela, Bergh Anders, Grönberg Henrik
Abstract excerpt
Frequent loss of heterogeneity in prostate cancer cells and linkage studies of families affected by hereditary prostate cancer (HPC) have implied that the short arm of chromosome 8, specifically 8p22-23, may harbor a prostate-cancer-susceptibility gene. In a recent study, seven potentially important mutations in the macrophage scavenger receptor 1 gene (MSR1), located at 8p22, were observed in families affected...
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