Article
Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 1999
Lange E M, Chen H, Brierley K, Perrone E E, Bock C H, Gillanders E, Ray M E, Cooney K A
Abstract excerpt
Several genetic epidemiological studies have provided data to support the hypothesis that there are genes on the X chromosome that may contribute to prostate cancer susceptibility. A recent linkage study of 360 prostate cancer families described evidence for a prostate cancer predisposition gene, termed HPCX, which maps to Xq27-28. To confirm the potential contribution of this locus to prostate cancer...
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