Article
Linkage of prostate cancer susceptibility loci to chromosome 1.
Human genetics - 1 Apr 2001
Xu J, Zheng S L, Chang B, Smith J R, Carpten J D, Stine O C, Isaacs S D, Wiley K E, Henning L, Ewing C, Bujnovszky P, Bleeker E R, Walsh P C, Trent J M, Meyers D A, Isaacs W B
Abstract excerpt
Three prostate cancer susceptibility genes have been reported to be linked to different regions on chromosome 1: HPC1 at 1q24-25, PCAP at 1q42-43, and CAPB at 1p36. Replication studies analyzing each of these regions have yielded inconsistent results. To evaluate linkage across this chromosome systematically, we performed multipoint linkage analyses with 50 microsatellite markers spanning chromosome 1 in 159...
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