Article
Reliability of non-invasively acquired human genomic DNA as a substrate for real-time PCR-assisted analysis of genetic polymorphisms.
Archives of toxicology - 1 Jul 2004
Neuhaus T, Geisen G, Bolt H M, Janzen V, Kraemer A, Vetter H, Ko Y
Abstract excerpt
Molecular epidemiological studies require high numbers of participants. The combination of an non-invasive access to human DNA with a rapid genotyping analysis, e.g. by use of LightCycler assisted real-time polymerase chain reaction (PCR), can be helpful in conducting such trials. The aim of our study was to define, for the first time, the use of LightCycler technology in analysis of non-invasively derived DNA....
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