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Article

Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy.

Molecular biology of the cell - 1 Feb 2003

Abeliovich Hagai, Zhang Chao, Dunn William A, Shokat Kevan M, Klionsky Daniel J

Abstract excerpt

Macroautophagy is a catabolic membrane trafficking phenomenon that is observed in all eukaryotic cells in response to various stimuli, such as nitrogen starvation and challenge with specific hormones. In the yeast Saccharomyces cerevisiae, the induction of autophagy involves a direct signal transduction mechanism that affects membrane dynamics. In this system, the induction process modifies a constitutive...

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Identifiers

PMID: 12589048
DOI: 10.1091/mbc.e02-07-0413
PMCID: PMC149986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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